Prolia can cause peripheral edema (fluid retention) or swelling, and this may lead to weight gain in some people. Examples of conditions Prolia is used off-label to treat include: Prolia is one option available to treat osteoporosis and reduce bone loss in people with a high risk for bone fracture. Theyll need to confirm that you arent pregnant. Increased risk of broken bones, including broken bones in the spine, after stopping, skipping or delaying Prolia. Prolia may cause several side effects. Vertigo (dizziness) was reported in some people who received Prolia for osteoporosis, but this was a less common side effect. Prolia injections administered by a healthcare professional. This is because its not known if Prolia is safe to receive while breastfeeding. Treating any mouth or dental problems early is the best way to help prevent serious dental complications. (Biosimilars are like generic drugs. The use of the eHealthMe site and its content is at your own risk. Keep out of the reach of children and pets. Prolia may be used off-label for RA, if you have a high risk for bone fractures. Prolia can cause many serious side effects. Prolia is sometimes used in people whose bone fracture is caused by certain medicines or cancer treatments. More than half of American adults take an herbal or dietary supplement, and many more use over-the-counter or prescription drugs to manage maladies ranging from the occasional headache to chronic health conditions or mood disorders.. For many, it is part of their daily routine. Your doctor will explain how Prolia will be given to you. Do not stop using this medicine without first talking to your doctor. may occur. For a detailed breakdown of Prolia versus Xgeva, check out this article. Osteoporosis medications and medication-related osteonecrosis of the jaw. Some people using Prolia have developed bone loss in the jaw, also called osteonecrosis of the jaw. The most common side effects of Prolia in patients with corticosteroid-induced osteoporosis are back pain, high blood pressure, lung infection (bronchitis), and headache. An allergic reaction is possible after using Prolia. Prolia contains the active ingredient denosumab. Your doctor may also have you take certain supplements that contain calcium and vitamin D while youre receiving Prolia. But, in some cases, alcohol can affect your balance and increase your risk for falls. Store in the original container away from heat and light. These factors include what your insurance plan covers. Theyll also usually treat the hypocalcemia right away. Tingling wasnt specifically reported as a side effect of Prolia in clinical trials. (2022). Drug class: miscellaneous bone resorption inhibitors. To learn more about this, see the How is Prolia administered? section below. Also tell them if you smoke, drink alcohol, or use illegal drugs. Use of the terms female and male in this article refers to sex assigned at birth. Prolia has active ingredients of denosumab. Learn more about the unique risk factors for osteoporosis in, Osteoporosis weakens bones, which leads to breaks in the hips, wrists, and spine. But if you think youre having a medical emergency, call 911 or your local emergency number. Copyright 1996-2023 Cerner Multum, Inc. Do not share this medicine with others. They do this by slowing the loss of minerals such as calcium from your bones. You may be interested in learning how Prolia compares to the medication Fosamax. These types of medications come in forms that are taken by mouth and forms that are given by injection. Weakness and tingling can also occur. If you plan to drink alcohol while using Prolia, ask your doctor how much is safe to drink. My GP (not the doctor who treats my osteoporosis) wondered if my early complete hysterectomy (I havent taken estrace in 15 years) and high dosage of thyroid I must take daily, effect the absorption of calcium? It is often used in osteoporosis. For example, if you have a serious UTI or other infection, call your doctor right away. Learn more about some of the side effects Prolia may cause. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Scientists use genetic rewiring to increase lifespan of cells, Beyond amyloid and tau: New targets in developing dementia treatments, Napping longer than 30 minutes linked to higher risk of obesity and high blood pressure, Activity 'snacks' could lower blood sugar, complication risk in type 1 diabetes, In Conversation: Investigating the power of music for dementia, 11 ways to increase bone density naturally, 14 of the best calcium supplements in 2023. Patients should not stop Prolia treatment without first consulting your Before you start Prolia treatment, your doctor will examine the inside of your mouth. They need to know if you have any of these conditions: This medicine is for injection under the skin. And theyll recommend if its the best option for your condition. Its a prescription drug thats used to treat osteoporosis and other forms of bone loss. How Viagra became a new 'tool' for young men, Ankylosing Spondylitis Pain: Fact or Fiction, https://www.ada.org/en/member-center/oral-health-topics/osteoporosis-medications, https://www.accessdata.fda.gov/drugsatfda_docs/label/2022/125320s210lbl.pdf, New clues to slow aging? Now i am worried that i've been taking K2 which also takes calcium from the blood to the bones. You should take calcium and vitamin D as your doctor tells you to while you receive Prolia. Your risk may also be higher if you: Stopping Prolia treatment can also increase your risk for bone fractures. Patient testimonials represent individual experiences with Prolia. Fracture in the spine after stopping Prolia treatment. You may have questions about Prolia and your treatment plan. Side effects are possible with Prolia use, but in most cases they go away after a while. Below are commonly used dosages, but the dosage you receive will be determined by your doctor. Call your doctor right away if you have signs of infection such as: swelling, pain, tenderness, warmth, or redness anywhere on your body; pain and burning when you urinate, painful urination; bladder infection (painful or difficult urination); lung infection (cough, shortness of breath); cold symptoms such as stuffy nose, sneezing, sore throat; This is not a complete list of side effects and others may occur. Prolia works by targeting a molecule called RANKL that osteoclasts need to work. Terms of Use. Some items may interact with your medicine. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. After your treatment with Prolia is stopped, or if you skip or delay taking a dose, your risk for breaking bones, including bones in your spine, is increased. This medicine is only given in a clinic, doctor's office, or other health care setting and will not be stored at home. If youd like to learn more about Prolia, talk with your doctor or pharmacist. Its a, Forteos active ingredient is teriparatide. Its recommended that you take 400 international units of vitamin D and 1,000 milligrams (mg) of calcium with Prolia. Symptoms of a mild allergic reaction can include: A more severe allergic reaction is rare but possible. Find out why people need calcium, which foods provide it, and what happens if they consume. Vitamin D The body needs vitamin D to absorb calcium. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. Studies have found that Prolia is generally safe and effective to treat osteoporosis and certain types of bone loss. Prolia and Xgeva both contain the active drug denosumab, but they are not approved to treat all of the same conditions. Follow your doctor's instructions. What is the most important information I should know about Prolia? Find out what it means, how its calculated, and more. Prolia is used in adults to treat osteoporosis or bone loss in people who: who cannot use another osteoporosis medicine or these medicines did not work well. This aids in keeping your calcium level within the recommended range. This increases your risk for bone fractures. Dizziness from Prolia is usually mild and may go away on its own within a few days or weeks. Symptoms of a fracture include new or unusual pain in your hip, groin, or thigh. If you are a healthcare professional, click "I Agree" to continue. NOTE: This medicine is only for you. Having a tooth extraction while youre using Prolia may increase your risk for these side effects. Theyll discuss with you other treatments to help prevent bone loss. If you need to have any dental work (especially surgery), tell the dentist ahead of time that you are using Prolia. For this reason, some calcium supplements are combined with vitamin D. This vitamin is available in two forms, vitamin D 2 (ergocalciferol) and vitamin for prostate cancer that has not spread to other parts of the body. If youd like a detailed comparison of Prolia versus Boniva, view this article. 2023 Healthline Media UK Ltd, Brighton, UK. The drug stays in your system and continues to slow bone breakdown over this period of time. Yoga for Osteoporosis: 5 Beneficial Poses, Diet and Osteoporosis: Nutrients, Diet Tips, and More. Call your doctor for medical advice about side effects. Call your doctor or health care professional if you are unable to keep an appointment. Our phase IV clinical studies alone cannot establish cause-effect relationship. This is because your body doesnt make enough bone, or it loses bone faster than it makes new bone. If you have questions about how to pay for your prescription, talk with your doctor or pharmacist. Tingling or numbness in the hands, feet, and face can develop as a symptom of severe hypocalcemia. As you age, your BMD is reduced, and this may increase your risk for osteoporosis. Ask your doctor about your own risk. Q: Does AlgaePlus Increase Bone Mass? Prolia is a medicine that may affect the ability of your body to fight infections. It strengthens your bones by stopping certain bone cells called osteoclasts from breaking down your bones. Tell your doctor right away if you become pregnant while taking Prolia. WebProlia is used to treat osteoporosis in women after menopause and in men, and in people How long will the side effects of Prolia last? Over time, Prolia helps to improve the density and strength of your bones by slowing bone loss. Youll receive Prolia from a healthcare professional as an injection under the skin in one of the following areas: Prolia contains the active drug denosumab, which is a biologic medication. Its important to practice good oral hygiene during Prolia treatment. (With off-label use, a drug is used to treat conditions other than those its been approved to treat.). You should not receive Prolia if you are allergic to denosumab, or if you have: low levels of calcium in your blood (hypocalcemia); or; if you are pregnant. have happened in people who take Prolia. In fact, bone breakdown is higher in the first several months after you stop Prolia. After you stop taking Prolia, youre more likely to experience bone loss, and your risk of a vertebral fracture increases. With osteoporosis, your bones become porous, meaning there are large holes within your bone tissue. Yes, if recommended by your doctor, you can stop taking Prolia. But if they become bothersome, talk with your doctor or pharmacist. But its not clear whether this side effect occurred in clinical studies. You may be more likely to develop osteonecrosis of the jaw if you have cancer or have been treated with chemotherapy, radiation, or steroids. Boniva contains the active drug ibandronate, but Prolia contains the active drug denosumab. Mild side effects of Prolia that have been reported include: Mild side effects of many drugs may go away within a few days or a few weeks. It is created by eHealthMe based on reports of 8,432 people who take Prolia and Calcium from the FDA, and is updated regularly. The most common medications prescribed to lower cholesterol are statins. If youre able to become pregnant, your doctor will have you take a pregnancy test before you start Prolia treatment. Call your doctor for medical advice about side effects. This is called hypocalcemia. Prolia is injected under the skin. Advertising on our site helps support our mission. To learn how Prolia and Tymlos are alike and different, see this comparison. You should not breastfeed while using this medicine. This may include acetaminophen (Tylenol), naproxen (Aleve), or ibuprofen (Advil, Motrin). Thyroid or parathyroid surgery. Hair loss with Prolia was reported after the drugs initial studies were done and it was approved for use. Some research has shown that alcohol consumption may increase your risk of osteoporosis, a bone fracture or impaired healing after a fracture. Patients in the study may take other drugs besides Prolia and Calcium. You may wonder how Prolia compares to the medication Zometa. The most common side effects of Prolia in patients receiving certain treatments for prostate or breast cancer are joint pain, back pain, pain in your arms and legs, and muscle pain. This is not a complete list of warnings for Prolia. Calcium and Vitamin D: A major role of vitamin D is to help the body absorb calcium and maintain bone density. Not getting enough calcium in your diet can lead to fragile, brittle bones that are more prone to fractures and disease. Note: After the Food and Drug Administration (FDA) approves a drug, it tracks and reviews side effects of the medication. If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date. Prolia is a prescription medicine used to treat osteoporosis in men and women who will be taking corticosteroid medicines (such as prednisone) for at least six months and are at high risk for fracture. Prolia contains the active drug denosumab, while Tymlos contains the active drug abaloparatide. Your doctor should examine your mouth before you start Prolia and may tell you to see your dentist. It could harm the unborn baby or cause birth defects. Continue reading, Prolia (denosumab) does increase bone density. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses. But unlike generics, which are made for nonbiologic drugs, biosimilars are made for biologic drugs.). You may take the carton out of the refrigerator and allow it to reach room temperature before the injection is given.
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